Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial

BACKGROUND: The interaction between thrombosis and inflammation appears central to COVID-19-associated coagulopathy and likely contributes to poor outcomes. Tissue factor is a driver of disordered coagulation and inflammatory signaling in viral infections and is important for viral replication; ther...

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Autores principales: Hess, Connie N., Capell, Warren H., Bristow, Michael R., Ruf, Wolfram, Szarek, Michael, Morrow, David A., Nicolau, Jose C., Graybill, Christopher A., Marshall, Debra, Hsia, Judith, Bonaca, Marc P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Trial Designs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720379/
https://www.ncbi.nlm.nih.gov/pubmed/34986394
http://dx.doi.org/10.1016/j.ahj.2021.12.010

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