A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

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Effective small molecule therapies to combat the SARS-CoV-2 infection are still lacking as the COVID-19 pandemic continues globally. High throughput screening assays are needed for lead discovery and optimization of small molecule SARS-CoV-2 inhibitors. In this work, we have applied viral pseudotypi...

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Detalles Bibliográficos
Autores principales: Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Shen, Min, Guo, Hui, Zhu, Wei, Klumpp-Thomas, Carleen, Michael, Sam, Itkin, Misha, Itkin, Zina, Straus, Marco R., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R., Chen, Catherine Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. on behalf of Society for Laboratory Automation and Screening. 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720380/
https://www.ncbi.nlm.nih.gov/pubmed/35086793
http://dx.doi.org/10.1016/j.slasd.2021.12.005
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