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Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report

BACKGROUND: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. CASE DESCRIPTION: We present the case of a 66-year-old man who presented with altered mental status an...

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Detalles Bibliográficos
Autores principales: Hess, Ryan M., Khan, Asham, Edwards, Mallory, Siddiqui, Adnan H., Levy, Elad I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720421/
https://www.ncbi.nlm.nih.gov/pubmed/34992900
http://dx.doi.org/10.25259/SNI_1036_2021
Descripción
Sumario:BACKGROUND: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. CASE DESCRIPTION: We present the case of a 66-year-old man who presented with altered mental status and progressively became comatose. He was found to have fulminant ventriculitis due to a ruptured intracranial abscess. He was treated with bilateral IRRAflow® catheter (IRRAS, Stockholm, Sweden) placement through which continuous irrigation with vancomycin was initiated. CONCLUSION: This treatment was safe and led to improvement in the patient’s neurologic examination, imaging findings, and cerebrospinal fluid profiles.