Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report

BACKGROUND: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. CASE DESCRIPTION: We present the case of a 66-year-old man who presented with altered mental status an...

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Autores principales: Hess, Ryan M., Khan, Asham, Edwards, Mallory, Siddiqui, Adnan H., Levy, Elad I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720421/
https://www.ncbi.nlm.nih.gov/pubmed/34992900
http://dx.doi.org/10.25259/SNI_1036_2021
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author Hess, Ryan M.
Khan, Asham
Edwards, Mallory
Siddiqui, Adnan H.
Levy, Elad I.
author_facet Hess, Ryan M.
Khan, Asham
Edwards, Mallory
Siddiqui, Adnan H.
Levy, Elad I.
author_sort Hess, Ryan M.
collection PubMed
description BACKGROUND: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. CASE DESCRIPTION: We present the case of a 66-year-old man who presented with altered mental status and progressively became comatose. He was found to have fulminant ventriculitis due to a ruptured intracranial abscess. He was treated with bilateral IRRAflow® catheter (IRRAS, Stockholm, Sweden) placement through which continuous irrigation with vancomycin was initiated. CONCLUSION: This treatment was safe and led to improvement in the patient’s neurologic examination, imaging findings, and cerebrospinal fluid profiles.
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spelling pubmed-87204212022-01-05 Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report Hess, Ryan M. Khan, Asham Edwards, Mallory Siddiqui, Adnan H. Levy, Elad I. Surg Neurol Int Case Report BACKGROUND: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. CASE DESCRIPTION: We present the case of a 66-year-old man who presented with altered mental status and progressively became comatose. He was found to have fulminant ventriculitis due to a ruptured intracranial abscess. He was treated with bilateral IRRAflow® catheter (IRRAS, Stockholm, Sweden) placement through which continuous irrigation with vancomycin was initiated. CONCLUSION: This treatment was safe and led to improvement in the patient’s neurologic examination, imaging findings, and cerebrospinal fluid profiles. Scientific Scholar 2021-11-30 /pmc/articles/PMC8720421/ /pubmed/34992900 http://dx.doi.org/10.25259/SNI_1036_2021 Text en Copyright: © 2021 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Hess, Ryan M.
Khan, Asham
Edwards, Mallory
Siddiqui, Adnan H.
Levy, Elad I.
Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
title Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
title_full Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
title_fullStr Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
title_full_unstemmed Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
title_short Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
title_sort continuous intraventricular vancomycin for treatment of ventriculitis using irraflow®: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720421/
https://www.ncbi.nlm.nih.gov/pubmed/34992900
http://dx.doi.org/10.25259/SNI_1036_2021
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