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Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation

BACKGROUND: Glioblastoma is the most common glioma presenting within adults with an incidence of 10 per 100,000 people globally. These are mostly supratentorial tumors with rare cases of extra-axial spread. Even rarer is the presentation of glioblastoma within the cerebellopontine angle (CPA). Here,...

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Autores principales: Bajwa, Mohammad Hamza, Ul Islam, Mohammad Yousuf, Bukhari, Syed Sarmad, Khan, Ahsan Ali, Ahmad, Zubair, Enam, Syed Ather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720425/
https://www.ncbi.nlm.nih.gov/pubmed/34992903
http://dx.doi.org/10.25259/SNI_684_2021
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author Bajwa, Mohammad Hamza
Ul Islam, Mohammad Yousuf
Bukhari, Syed Sarmad
Khan, Ahsan Ali
Ahmad, Zubair
Enam, Syed Ather
author_facet Bajwa, Mohammad Hamza
Ul Islam, Mohammad Yousuf
Bukhari, Syed Sarmad
Khan, Ahsan Ali
Ahmad, Zubair
Enam, Syed Ather
author_sort Bajwa, Mohammad Hamza
collection PubMed
description BACKGROUND: Glioblastoma is the most common glioma presenting within adults with an incidence of 10 per 100,000 people globally. These are mostly supratentorial tumors with rare cases of extra-axial spread. Even rarer is the presentation of glioblastoma within the cerebellopontine angle (CPA). Here, we present a case of a previously resected and irradiated glioblastoma metastasizing from the right temporal lobe region to the contralateral CPA. CASE DESCRIPTION: A 24-year-old female who previously underwent surgery and concurrent chemoradiotherapy for a right temporal glioblastoma in August 2020, presented to us 6 months later with headaches, vomiting, and dizziness for the past 6 days. She had left-sided dysmetria on examination. MRI of the brain showed an extra-axial, heterogeneously enhancing lesion within the left CPA. The patient subsequently underwent a left retrosigmoid craniotomy and maximum safe resection of the lesion. Histopathology reported the lesion as a glioblastoma. CONCLUSION: Glioblastoma within the CPA is rarely reported within the literature. To date, our case is the first instance of an extra-axial contralateral metastasis of glioblastoma.
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spelling pubmed-87204252022-01-05 Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation Bajwa, Mohammad Hamza Ul Islam, Mohammad Yousuf Bukhari, Syed Sarmad Khan, Ahsan Ali Ahmad, Zubair Enam, Syed Ather Surg Neurol Int Case Report BACKGROUND: Glioblastoma is the most common glioma presenting within adults with an incidence of 10 per 100,000 people globally. These are mostly supratentorial tumors with rare cases of extra-axial spread. Even rarer is the presentation of glioblastoma within the cerebellopontine angle (CPA). Here, we present a case of a previously resected and irradiated glioblastoma metastasizing from the right temporal lobe region to the contralateral CPA. CASE DESCRIPTION: A 24-year-old female who previously underwent surgery and concurrent chemoradiotherapy for a right temporal glioblastoma in August 2020, presented to us 6 months later with headaches, vomiting, and dizziness for the past 6 days. She had left-sided dysmetria on examination. MRI of the brain showed an extra-axial, heterogeneously enhancing lesion within the left CPA. The patient subsequently underwent a left retrosigmoid craniotomy and maximum safe resection of the lesion. Histopathology reported the lesion as a glioblastoma. CONCLUSION: Glioblastoma within the CPA is rarely reported within the literature. To date, our case is the first instance of an extra-axial contralateral metastasis of glioblastoma. Scientific Scholar 2021-11-30 /pmc/articles/PMC8720425/ /pubmed/34992903 http://dx.doi.org/10.25259/SNI_684_2021 Text en Copyright: © 2021 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bajwa, Mohammad Hamza
Ul Islam, Mohammad Yousuf
Bukhari, Syed Sarmad
Khan, Ahsan Ali
Ahmad, Zubair
Enam, Syed Ather
Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation
title Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation
title_full Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation
title_fullStr Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation
title_full_unstemmed Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation
title_short Contralateral metastatic cerebellopontine angle glioblastoma: A rare manifestation
title_sort contralateral metastatic cerebellopontine angle glioblastoma: a rare manifestation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720425/
https://www.ncbi.nlm.nih.gov/pubmed/34992903
http://dx.doi.org/10.25259/SNI_684_2021
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