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Spinal cord detethering without laminectomy or laminotomy

BACKGROUND: Tethered cord syndrome occurs when there is abnormal tension on the distal spinal cord, which limits its elevation as patients grow. This results in stretching of the neural elements and microvasculature, resulting in both direct and ischemic injury.[7] Animal studies suggest that impair...

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Autores principales: Housley, Steven B., Patel, Devan, Nyabuto, Elizabeth, Reynolds, Renée M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720436/
https://www.ncbi.nlm.nih.gov/pubmed/34992926
http://dx.doi.org/10.25259/SNI_942_2021
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author Housley, Steven B.
Patel, Devan
Nyabuto, Elizabeth
Reynolds, Renée M.
author_facet Housley, Steven B.
Patel, Devan
Nyabuto, Elizabeth
Reynolds, Renée M.
author_sort Housley, Steven B.
collection PubMed
description BACKGROUND: Tethered cord syndrome occurs when there is abnormal tension on the distal spinal cord, which limits its elevation as patients grow. This results in stretching of the neural elements and microvasculature, resulting in both direct and ischemic injury.[7] Animal studies suggest that impairment of oxidative metabolic pathways may contribute to neuronal injury.[7] Associated conditions include myelomeningocele, lipomyelomeningocele, intraspinal lipomas, diastematomyelia, thickened/fatty filum terminale, and trauma.[2] Tethering may be asymptomatic or result in a variety of symptoms including lower extremity weakness/sensory deficits, bowel/bladder dysfunction, scoliosis, pes cavus, and back/leg pain.[6] Early surgical intervention has been shown to improve outcomes and may be performed prophylactically or to prevent symptom progression.[1,3] More specifically, retrospective studies demonstrate that surgical intervention in patients under the age of 2 years is associated with improved outcomes.[5] In some cases, detethering may result in clinical improvement.[3] CASE DESCRIPTION: We present a case of a 6-month-old male with a low-lying conus medullaris, lumbar syrinx, mildly abnormal urodynamic studies, and asymmetric utilization of his lower extremities observed during the evaluation of a Y-shaped gluteal cleft. He underwent elective spinal cord detethering via the safe and effective, minimally invasive technique described in the video. The patient’s parents gave informed consent for treatment and video recording. Institutional review board approval was deemed unnecessary. CONCLUSION: Given the variety of surgical techniques used for cord detethering, this video may assist other surgeons in developing techniques that require little to no compromise of the developing bony spinal column while achieving sufficient release of the spinal cord.[4]
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spelling pubmed-87204362022-01-05 Spinal cord detethering without laminectomy or laminotomy Housley, Steven B. Patel, Devan Nyabuto, Elizabeth Reynolds, Renée M. Surg Neurol Int Video Abstract BACKGROUND: Tethered cord syndrome occurs when there is abnormal tension on the distal spinal cord, which limits its elevation as patients grow. This results in stretching of the neural elements and microvasculature, resulting in both direct and ischemic injury.[7] Animal studies suggest that impairment of oxidative metabolic pathways may contribute to neuronal injury.[7] Associated conditions include myelomeningocele, lipomyelomeningocele, intraspinal lipomas, diastematomyelia, thickened/fatty filum terminale, and trauma.[2] Tethering may be asymptomatic or result in a variety of symptoms including lower extremity weakness/sensory deficits, bowel/bladder dysfunction, scoliosis, pes cavus, and back/leg pain.[6] Early surgical intervention has been shown to improve outcomes and may be performed prophylactically or to prevent symptom progression.[1,3] More specifically, retrospective studies demonstrate that surgical intervention in patients under the age of 2 years is associated with improved outcomes.[5] In some cases, detethering may result in clinical improvement.[3] CASE DESCRIPTION: We present a case of a 6-month-old male with a low-lying conus medullaris, lumbar syrinx, mildly abnormal urodynamic studies, and asymmetric utilization of his lower extremities observed during the evaluation of a Y-shaped gluteal cleft. He underwent elective spinal cord detethering via the safe and effective, minimally invasive technique described in the video. The patient’s parents gave informed consent for treatment and video recording. Institutional review board approval was deemed unnecessary. CONCLUSION: Given the variety of surgical techniques used for cord detethering, this video may assist other surgeons in developing techniques that require little to no compromise of the developing bony spinal column while achieving sufficient release of the spinal cord.[4] Scientific Scholar 2021-12-14 /pmc/articles/PMC8720436/ /pubmed/34992926 http://dx.doi.org/10.25259/SNI_942_2021 Text en Copyright: © 2021 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Video Abstract
Housley, Steven B.
Patel, Devan
Nyabuto, Elizabeth
Reynolds, Renée M.
Spinal cord detethering without laminectomy or laminotomy
title Spinal cord detethering without laminectomy or laminotomy
title_full Spinal cord detethering without laminectomy or laminotomy
title_fullStr Spinal cord detethering without laminectomy or laminotomy
title_full_unstemmed Spinal cord detethering without laminectomy or laminotomy
title_short Spinal cord detethering without laminectomy or laminotomy
title_sort spinal cord detethering without laminectomy or laminotomy
topic Video Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720436/
https://www.ncbi.nlm.nih.gov/pubmed/34992926
http://dx.doi.org/10.25259/SNI_942_2021
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