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Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review
BACKGROUND: Primary spinal extramedullary germ cell tumor are very rare. Germ cell tumor are similar histologically to germ cells of genital organs and may arise rarely from central and peripheral nervous system. CASE DESCRIPTION: We report a case of 20-year-old male who presented with progressive l...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientific Scholar
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720437/ https://www.ncbi.nlm.nih.gov/pubmed/34992920 http://dx.doi.org/10.25259/SNI_575_2021 |
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author | Vij, Mukesh Bhardwaj, Sandeep |
author_facet | Vij, Mukesh Bhardwaj, Sandeep |
author_sort | Vij, Mukesh |
collection | PubMed |
description | BACKGROUND: Primary spinal extramedullary germ cell tumor are very rare. Germ cell tumor are similar histologically to germ cells of genital organs and may arise rarely from central and peripheral nervous system. CASE DESCRIPTION: We report a case of 20-year-old male who presented with progressive lower extremity weakness, spasticity, and numbness of legs. Patient was evaluated with magnetic resonance imaging dorsal spine which revealed extramedullary mass in dorsal (D2-D3) level with severe cord compression. Tumor was found to be extramedullary with histopathology consistent with germ cell tumor. Patient was given radiotherapy and chemotherapy postoperatively. CONCLUSION: Primary spinal extramedullary germ cell tumors are very rare and are very sensitive to radiation and chemotherapy. Various management and treatment protocols are available across institutions in the world. We recommend adequate decompression of cord with biopsy followed by local radiation and chemotherapy. As these are rare tumors, presenting with significant neurological deficits should always be kept in the differential diagnosis. |
format | Online Article Text |
id | pubmed-8720437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Scientific Scholar |
record_format | MEDLINE/PubMed |
spelling | pubmed-87204372022-01-05 Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review Vij, Mukesh Bhardwaj, Sandeep Surg Neurol Int Case Report BACKGROUND: Primary spinal extramedullary germ cell tumor are very rare. Germ cell tumor are similar histologically to germ cells of genital organs and may arise rarely from central and peripheral nervous system. CASE DESCRIPTION: We report a case of 20-year-old male who presented with progressive lower extremity weakness, spasticity, and numbness of legs. Patient was evaluated with magnetic resonance imaging dorsal spine which revealed extramedullary mass in dorsal (D2-D3) level with severe cord compression. Tumor was found to be extramedullary with histopathology consistent with germ cell tumor. Patient was given radiotherapy and chemotherapy postoperatively. CONCLUSION: Primary spinal extramedullary germ cell tumors are very rare and are very sensitive to radiation and chemotherapy. Various management and treatment protocols are available across institutions in the world. We recommend adequate decompression of cord with biopsy followed by local radiation and chemotherapy. As these are rare tumors, presenting with significant neurological deficits should always be kept in the differential diagnosis. Scientific Scholar 2021-12-08 /pmc/articles/PMC8720437/ /pubmed/34992920 http://dx.doi.org/10.25259/SNI_575_2021 Text en Copyright: © 2021 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Vij, Mukesh Bhardwaj, Sandeep Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review |
title | Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review |
title_full | Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review |
title_fullStr | Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review |
title_full_unstemmed | Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review |
title_short | Primary spinal dorsal extramedullary germ cell tumor: A rare case report and literature review |
title_sort | primary spinal dorsal extramedullary germ cell tumor: a rare case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720437/ https://www.ncbi.nlm.nih.gov/pubmed/34992920 http://dx.doi.org/10.25259/SNI_575_2021 |
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