RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma

Glioblastoma, the most aggressive form of malignant glioma, is very difficult to treat because of its aggressively invasive nature and high recurrence rates. RAS-selective lethal 3 (RSL3), a well-known inhibitor of glutathione peroxidase 4 (GPX4), could effectively induce oxidative cell death in gli...

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Detalles Bibliográficos
Autores principales: Li, Shengbiao, He, Yuping, Chen, Kexin, Sun, Jiaojiao, Zhang, Lulu, He, Yaxin, Yu, Hong, Li, Qiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720588/
https://www.ncbi.nlm.nih.gov/pubmed/34987700
http://dx.doi.org/10.1155/2021/2915019

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