Autophagic Flux Unleashes GATA4-NF-κB Axis to Promote Antioxidant Defense-Dependent Survival of Colorectal Cancer Cells under Chronic Acidosis

Solid tumors are usually associated with extracellular acidosis due to their increased dependence on glycolysis and poor vascularization. Cancer cells gradually become adapted to acidic microenvironment and even acquire increased aggressiveness. They are resistant to apoptosis but exhibit increased...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojie, Zhao, Minnan, Sun, Xue, Meng, Zhenzhen, Bai, Xiaojing, Gong, Yanchao, Xu, Limei, Hao, Xiaohe, Yang, Tingting, Wei, Zhao, Zhang, Xiyu, Guo, Haiyang, Li, Peishan, Liu, Qiao, Gong, Yaoqin, Shi, Yufang, Shao, Changshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720590/
https://www.ncbi.nlm.nih.gov/pubmed/34987705
http://dx.doi.org/10.1155/2021/8189485

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