Mettl5 mediated 18S rRNA N6-methyladenosine (m(6)A) modification controls stem cell fate determination and neural function

Ribosome RNA (rRNA) accounts for more than 80% of the cell's total RNA, while the physiological functions of rRNA modifications are poorly understood. Mutations of 18S rRNA m(6)A methyltransferase METTL5 cause intellectual disability, microcephaly, and facial dysmorphisms in patients, however,...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Liang, Yu, Lin, Rongzhi, Xiong, Qiuchan, Yu, Peng, Ma, Jieyi, Cheng, Maosheng, Han, Hui, Wang, Xiaochen, Wang, Ganping, Liang, Fengyin, Pei, Zhong, Chen, Demeng, Yuan, Quan, Jiang, Yi-Zhou, Lin, Shuibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720661/
https://www.ncbi.nlm.nih.gov/pubmed/35005123
http://dx.doi.org/10.1016/j.gendis.2020.07.004

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