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Osteopontin inhibits osteoarthritis progression via the OPN/CD44/PI3K signal axis
Chondrocyte degeneration and extracellular matrix component loss are the primary causes of osteoarthritis (OA). OA can be treated by inhibiting chondrocyte degeneration and increasing extracellular matrix component secretion. Osteopontin (OPN), a multifunctional protein, has gained immense attention...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720673/ https://www.ncbi.nlm.nih.gov/pubmed/35005113 http://dx.doi.org/10.1016/j.gendis.2020.06.006 |