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Lactate Upregulates the Expression of DNA Repair Genes, Causing Intrinsic Resistance of Cancer Cells to Cisplatin

Intrinsic or acquired drug resistance is one of the major problems compromising the success of antineoplastic treatments. Several evidences correlated some therapeutic failures with changes in cell metabolic asset and in line with these findings, hindering the glycolytic metabolism of cancer cells v...

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Detalles Bibliográficos
Autores principales:	Govoni, Marzia, Rossi, Valentina, Di Stefano, Giuseppina, Manerba, Marcella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pathology and Oncology Archive
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720744/ https://www.ncbi.nlm.nih.gov/pubmed/34987311 http://dx.doi.org/10.3389/pore.2021.1609951

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