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Decoding Conformational Imprint of Convoluted Molecular Interactions Between Prenylflavonoids and Aggregated Amyloid-Beta42 Peptide Causing Alzheimer’s Disease

Protein misfolding occurs due to the loss of native protein structure and adopts an abnormal structure, wherein the misfolded proteins accumulate and form aggregates, which result in the formation of amyloid fibrils that are associated with neurodegenerative diseases. Amyloid beta (Aβ42) aggregation...

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Detalles Bibliográficos
Autores principales: Srinivasan, E., Chandrasekhar, G., Chandrasekar, P., Anbarasu, K., Vickram, AS, Tayubi, Iftikhar Aslam, Rajasekaran, R., Karunakaran, Rohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720757/
https://www.ncbi.nlm.nih.gov/pubmed/34988060
http://dx.doi.org/10.3389/fchem.2021.753146