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Decoding Conformational Imprint of Convoluted Molecular Interactions Between Prenylflavonoids and Aggregated Amyloid-Beta42 Peptide Causing Alzheimer’s Disease
Protein misfolding occurs due to the loss of native protein structure and adopts an abnormal structure, wherein the misfolded proteins accumulate and form aggregates, which result in the formation of amyloid fibrils that are associated with neurodegenerative diseases. Amyloid beta (Aβ42) aggregation...
Autores principales: | Srinivasan, E., Chandrasekhar, G., Chandrasekar, P., Anbarasu, K., Vickram, AS, Tayubi, Iftikhar Aslam, Rajasekaran, R., Karunakaran, Rohini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720757/ https://www.ncbi.nlm.nih.gov/pubmed/34988060 http://dx.doi.org/10.3389/fchem.2021.753146 |
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