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Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the femoral head
Icariin is commonly used for the clinical treatment of osteonecrosis of the femoral head (ONFH). miR-23a-3p plays a vital role in regulating the osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs). The present study aimed to investigate the roles of icariin and miR-23a-3...
Autores principales: | Zhang, Xiao-yun, Li, Hua-nan, Chen, Feng, Chen, Yue-ping, Chai, Yuan, Liao, Jian-zhao, Gan, Bin, Chen, Ding-peng, Li, Song, Liu, Yong-qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720822/ https://www.ncbi.nlm.nih.gov/pubmed/35002378 http://dx.doi.org/10.1016/j.jsps.2021.10.009 |
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