Cargando…

Daratumumab Prevents Experimental Xenogeneic Graft-Versus-Host Disease by Skewing Proportions of T Cell Functional Subsets and Inhibiting T Cell Activation and Migration

Graft-versus-host disease (GVHD) remains the major cause of mortality and morbidity in non-relapse patients after allogeneic hematopoietic cell transplantation (allo-HCT). As the number of patients undergoing allo-HCT increases, it will become imperative to determine safe and effective treatment opt...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Yang, Shan, Wei, Gu, Tianning, Zhang, Jie, Wu, Yibo, Li, Xiaoqing, Zeng, Xiangjun, Zhou, Hongyu, Chen, Zhi, Xiao, Haowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720868/
https://www.ncbi.nlm.nih.gov/pubmed/34987512
http://dx.doi.org/10.3389/fimmu.2021.785774