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Daratumumab Prevents Experimental Xenogeneic Graft-Versus-Host Disease by Skewing Proportions of T Cell Functional Subsets and Inhibiting T Cell Activation and Migration
Graft-versus-host disease (GVHD) remains the major cause of mortality and morbidity in non-relapse patients after allogeneic hematopoietic cell transplantation (allo-HCT). As the number of patients undergoing allo-HCT increases, it will become imperative to determine safe and effective treatment opt...
Autores principales: | Gao, Yang, Shan, Wei, Gu, Tianning, Zhang, Jie, Wu, Yibo, Li, Xiaoqing, Zeng, Xiangjun, Zhou, Hongyu, Chen, Zhi, Xiao, Haowen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720868/ https://www.ncbi.nlm.nih.gov/pubmed/34987512 http://dx.doi.org/10.3389/fimmu.2021.785774 |
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