Exploring the Retinal Binding Cavity of Archaerhodopsin-3 by Replacing the Retinal Chromophore With a Dimethyl Phenylated Derivative

Rhodopsins act as photoreceptors with their chromophore retinal (vitamin-A aldehyde) and they regulate light-dependent biological functions. Archaerhodopsin-3 (AR3) is an outward proton pump that has been widely utilized as a tool for optogenetics, a method for controlling cellular activity by light...

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Detalles Bibliográficos
Autores principales: Tsuneishi, Taichi, Takahashi, Masataka, Tsujimura, Masaki, Kojima, Keiichi, Ishikita, Hiroshi, Takeuchi, Yasuo, Sudo, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721008/
https://www.ncbi.nlm.nih.gov/pubmed/34988122
http://dx.doi.org/10.3389/fmolb.2021.794948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721008/
https://www.ncbi.nlm.nih.gov/pubmed/34988122
http://dx.doi.org/10.3389/fmolb.2021.794948

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