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Exploring the Retinal Binding Cavity of Archaerhodopsin-3 by Replacing the Retinal Chromophore With a Dimethyl Phenylated Derivative
Rhodopsins act as photoreceptors with their chromophore retinal (vitamin-A aldehyde) and they regulate light-dependent biological functions. Archaerhodopsin-3 (AR3) is an outward proton pump that has been widely utilized as a tool for optogenetics, a method for controlling cellular activity by light...
Autores principales: | Tsuneishi, Taichi, Takahashi, Masataka, Tsujimura, Masaki, Kojima, Keiichi, Ishikita, Hiroshi, Takeuchi, Yasuo, Sudo, Yuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721008/ https://www.ncbi.nlm.nih.gov/pubmed/34988122 http://dx.doi.org/10.3389/fmolb.2021.794948 |
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