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Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis

There have been a number of advances in the clinical and translational understanding of cutaneous lupus and dermatomyositis, which both disproportionately affect women. These advances have involved ongoing collaborations between dermatology and rheumatology that highlight the importance of the skin...

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Autores principales: Werth, Victoria P., Askanase, Anca D., Lundberg, Ingrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721050/
https://www.ncbi.nlm.nih.gov/pubmed/35005178
http://dx.doi.org/10.1016/j.ijwd.2021.09.002
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author Werth, Victoria P.
Askanase, Anca D.
Lundberg, Ingrid E.
author_facet Werth, Victoria P.
Askanase, Anca D.
Lundberg, Ingrid E.
author_sort Werth, Victoria P.
collection PubMed
description There have been a number of advances in the clinical and translational understanding of cutaneous lupus and dermatomyositis, which both disproportionately affect women. These advances have involved ongoing collaborations between dermatology and rheumatology that highlight the importance of the skin in these disorders, with improvement in the education of trainees and clinical management of these complex multisystem diseases. In addition, a new disease classification has allowed inclusion of patients with skin-predominant dermatomyositis, frequently associated with systemic findings, in the spectrum of idiopathic inflammatory myopathies. Validated outcome measures allow translational research and facilitate progress toward better and more targeted therapeutics. Clinical trials using disease severity tools, such as the Cutaneous Lupus Erythematosus Area and Severity Index and the Cutaneous Dermatomyositis Disease Area and Severity Index, allow measurement of improvement in the skin. Recent results of phase 2 and 3 trials clearly show that patients will benefit from collaborative interactions and studies between dermatology and rheumatology.
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spelling pubmed-87210502022-01-07 Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis Werth, Victoria P. Askanase, Anca D. Lundberg, Ingrid E. Int J Womens Dermatol Review There have been a number of advances in the clinical and translational understanding of cutaneous lupus and dermatomyositis, which both disproportionately affect women. These advances have involved ongoing collaborations between dermatology and rheumatology that highlight the importance of the skin in these disorders, with improvement in the education of trainees and clinical management of these complex multisystem diseases. In addition, a new disease classification has allowed inclusion of patients with skin-predominant dermatomyositis, frequently associated with systemic findings, in the spectrum of idiopathic inflammatory myopathies. Validated outcome measures allow translational research and facilitate progress toward better and more targeted therapeutics. Clinical trials using disease severity tools, such as the Cutaneous Lupus Erythematosus Area and Severity Index and the Cutaneous Dermatomyositis Disease Area and Severity Index, allow measurement of improvement in the skin. Recent results of phase 2 and 3 trials clearly show that patients will benefit from collaborative interactions and studies between dermatology and rheumatology. Elsevier 2021-09-24 /pmc/articles/PMC8721050/ /pubmed/35005178 http://dx.doi.org/10.1016/j.ijwd.2021.09.002 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Werth, Victoria P.
Askanase, Anca D.
Lundberg, Ingrid E.
Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
title Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
title_full Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
title_fullStr Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
title_full_unstemmed Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
title_short Importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
title_sort importance of collaboration of dermatology and rheumatology to advance the field for lupus and dermatomyositis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721050/
https://www.ncbi.nlm.nih.gov/pubmed/35005178
http://dx.doi.org/10.1016/j.ijwd.2021.09.002
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