Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious adverse cutaneous drug reactions, characterized by epidermal detachment and mucous membrane involvement. SJS/TEN is more common in female patients, with unique findings in the ocular and vulvar regions. Early recognition...

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Detalles Bibliográficos
Autores principales: Magone, M. Teresa, Maiberger, Mary, Clayton, Janine, Pasieka, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721055/
https://www.ncbi.nlm.nih.gov/pubmed/35024409
http://dx.doi.org/10.1016/j.ijwd.2021.08.012
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author Magone, M. Teresa
Maiberger, Mary
Clayton, Janine
Pasieka, Helena
author_facet Magone, M. Teresa
Maiberger, Mary
Clayton, Janine
Pasieka, Helena
author_sort Magone, M. Teresa
collection PubMed
description Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious adverse cutaneous drug reactions, characterized by epidermal detachment and mucous membrane involvement. SJS/TEN is more common in female patients, with unique findings in the ocular and vulvar regions. Early recognition and intervention, as well as long-term follow-up, are crucial to prevent devastating scarring and sequelae. This review examines the vulvar and ocular manifestations of SJS/TEN and describes the current treatment recommendations for female patients, requiring close consultation and collaboration among dermatology, ophthalmology, and gynecology.
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spelling pubmed-87210552022-01-11 Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review Magone, M. Teresa Maiberger, Mary Clayton, Janine Pasieka, Helena Int J Womens Dermatol Article Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious adverse cutaneous drug reactions, characterized by epidermal detachment and mucous membrane involvement. SJS/TEN is more common in female patients, with unique findings in the ocular and vulvar regions. Early recognition and intervention, as well as long-term follow-up, are crucial to prevent devastating scarring and sequelae. This review examines the vulvar and ocular manifestations of SJS/TEN and describes the current treatment recommendations for female patients, requiring close consultation and collaboration among dermatology, ophthalmology, and gynecology. Elsevier 2021-09-02 /pmc/articles/PMC8721055/ /pubmed/35024409 http://dx.doi.org/10.1016/j.ijwd.2021.08.012 Text en © 2021 Published by Elsevier Inc. on behalf of Women's Dermatologic Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Magone, M. Teresa
Maiberger, Mary
Clayton, Janine
Pasieka, Helena
Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review
title Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review
title_full Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review
title_fullStr Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review
title_full_unstemmed Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review
title_short Vulvovaginal and ocular involvement and treatment in female patients with Stevens–Johnson syndrome and toxic epidermal necrolysis: A review
title_sort vulvovaginal and ocular involvement and treatment in female patients with stevens–johnson syndrome and toxic epidermal necrolysis: a review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721055/
https://www.ncbi.nlm.nih.gov/pubmed/35024409
http://dx.doi.org/10.1016/j.ijwd.2021.08.012
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