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Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis

Hypoxia contributes to the progression and metastasis of lung adenocarcinoma (LUAD). However, the specific underlying molecular mechanisms have not been fully elucidated. Here we report that Notch4 is upregulated in lung tissue from lung cancer patients. Functionally, Hypoxia activates the expressio...

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Detalles Bibliográficos
Autores principales:	Li, Xiaochen, Cao, Xiaopei, Zhao, Hanqiu, Guo, Mingzhou, Fang, Xiaoyu, Li, Ke, Qin, Lu, He, Yuanzhou, Liu, Xiansheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721100/ https://www.ncbi.nlm.nih.gov/pubmed/34988077 http://dx.doi.org/10.3389/fcell.2021.780121

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