Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3–PEX19 Interaction

Human pathogenic trypanosomatid parasites harbor a unique form of peroxisomes termed glycosomes that are essential for parasite viability. We and others previously identified and characterized the essential Trypanosoma brucei ortholog TbPEX3, which is the membrane-docking factor for the cytosolic re...

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Detalles Bibliográficos
Autores principales: Li, Mengqiao, Gaussmann, Stefan, Tippler, Bettina, Ott, Julia, Popowicz, Grzegorz M, Schliebs, Wolfgang, Sattler, Michael, Erdmann, Ralf, Kalel, Vishal C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721105/
https://www.ncbi.nlm.nih.gov/pubmed/34988071
http://dx.doi.org/10.3389/fcell.2021.737159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721105/
https://www.ncbi.nlm.nih.gov/pubmed/34988071
http://dx.doi.org/10.3389/fcell.2021.737159

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