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Indirect Pathway Metabolic Engineering Strategies for Enhanced Biosynthesis of Hyaluronic Acid in Engineered Corynebacterium glutamicum

Hyaluronic acid (HA) is composed of alternating d-glucuronic acid and N-acetyl-d-glucosamine, with excellent biocompatibility and water retention capacity. To achieve heterologous biosynthesis of HA, Corynebacterium glutamicum, a safe GRAS (generally recognized as safe) host, was utilized and metabo...

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Detalles Bibliográficos
Autores principales:	Du, Yan, Cheng, Fangyu, Wang, Miaomiao, Xu, Chunmeng, Yu, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721151/ https://www.ncbi.nlm.nih.gov/pubmed/34988066 http://dx.doi.org/10.3389/fbioe.2021.768490

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