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Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw
Few cases of spontaneous bone regeneration after extensive resection of the jaw bone have been reported, but it is more common in young adults or children. In this case, we report spontaneous bone healing in a 73-year-old female patient. On radiological examination, necrotic regions were seen in the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Oral and Maxillofacial Surgeons
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721417/ https://www.ncbi.nlm.nih.gov/pubmed/34969020 http://dx.doi.org/10.5125/jkaoms.2021.47.6.465 |
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author | Esen, Alparslan Gurses, Gokhan Akkulah, Sebnem |
author_facet | Esen, Alparslan Gurses, Gokhan Akkulah, Sebnem |
author_sort | Esen, Alparslan |
collection | PubMed |
description | Few cases of spontaneous bone regeneration after extensive resection of the jaw bone have been reported, but it is more common in young adults or children. In this case, we report spontaneous bone healing in a 73-year-old female patient. On radiological examination, necrotic regions were seen in the right mandible. She was diagnosed with medication-related osteonecrosis of the jaw due to previous bisphosphonate use. After segmental resection, stabilization achieved using a reconstruction plate. The periosteum was preserved during the procedure. Twelve months later, panoramic radiography was taken and bone formation was seen both horizontally and vertically around the plate. If the periosteum is preserved and stabilization is achieved after resection in benign lesions, the bone may regenerate spontaneously regardless of age. Therefore, instead of simultaneous autogenous bone application, such patients may be followed to determine whether spontaneous bone healing will occur. This should improve patient comfort and reduce surgical cost. |
format | Online Article Text |
id | pubmed-8721417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Association of Oral and Maxillofacial Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-87214172022-01-11 Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw Esen, Alparslan Gurses, Gokhan Akkulah, Sebnem J Korean Assoc Oral Maxillofac Surg Case Report Few cases of spontaneous bone regeneration after extensive resection of the jaw bone have been reported, but it is more common in young adults or children. In this case, we report spontaneous bone healing in a 73-year-old female patient. On radiological examination, necrotic regions were seen in the right mandible. She was diagnosed with medication-related osteonecrosis of the jaw due to previous bisphosphonate use. After segmental resection, stabilization achieved using a reconstruction plate. The periosteum was preserved during the procedure. Twelve months later, panoramic radiography was taken and bone formation was seen both horizontally and vertically around the plate. If the periosteum is preserved and stabilization is achieved after resection in benign lesions, the bone may regenerate spontaneously regardless of age. Therefore, instead of simultaneous autogenous bone application, such patients may be followed to determine whether spontaneous bone healing will occur. This should improve patient comfort and reduce surgical cost. The Korean Association of Oral and Maxillofacial Surgeons 2021-12-31 2021-12-31 /pmc/articles/PMC8721417/ /pubmed/34969020 http://dx.doi.org/10.5125/jkaoms.2021.47.6.465 Text en Copyright © 2021 The Korean Association of Oral and Maxillofacial Surgeons. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Esen, Alparslan Gurses, Gokhan Akkulah, Sebnem Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
title | Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
title_full | Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
title_fullStr | Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
title_full_unstemmed | Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
title_short | Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
title_sort | spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721417/ https://www.ncbi.nlm.nih.gov/pubmed/34969020 http://dx.doi.org/10.5125/jkaoms.2021.47.6.465 |
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