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GM-CSF impairs erythropoiesis by disrupting erythroblastic island formation via macrophages
Anemia is a significant complication of chronic inflammation and may be related to dysregulated activities among erythroblastic island (EBI) macrophages. GM-CSF was reported to be upregulated and attracted as a therapeutic target in many inflammatory diseases. Among EBIs, we found that the GM-CSF re...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721478/ https://www.ncbi.nlm.nih.gov/pubmed/34980171 http://dx.doi.org/10.1186/s12967-021-03214-5 |