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Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial

BACKGROUND: SARS-CoV-2 seems to affect the regulation of pulmonary perfusion. Hypoperfusion in areas of well-aerated lung parenchyma results in a ventilation–perfusion mismatch that can be characterized using subtraction computed tomography angiography (sCTA). This study aims to evaluate the efficac...

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Detalles Bibliográficos
Autores principales: Santamarina, Mario G., Beddings, Ignacio, Lomakin, Felipe Martinez, Boisier Riscal, Dominique, Gutiérrez Claveria, Mónica, Vidal Marambio, Jaime, Retamal Báez, Nicole, Pavez Novoa, Cristian, Reyes Allende, César, Ferreira Perey, Paulina, Gutiérrez Torres, Miguel, Villalobos Mazza, Camila, Vergara Sagredo, Constanza, Ahumada Bermejo, Sebastian, Labarca Mellado, Eduardo, Barthel Munchmeyer, Elizabeth, Marchant Ramos, Solange, Volpacchio, Mariano, Vega, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721481/
https://www.ncbi.nlm.nih.gov/pubmed/34980198
http://dx.doi.org/10.1186/s13054-021-03885-y

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