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α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis

A previously validated anti-rheumatic compound α-mangostin (MAN) shows significant metabolism regulatory effects. The current study aimed to clarify whether this property contributed to its inhibition on synovial angiogenesis. Male wistar rats with adjuvant-induced arthritis (AIA) were orally treate...

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Detalles Bibliográficos
Autores principales: Jiang, Tian-Tian, Ji, Chao-Fan, Cheng, Xiu-Ping, Gu, Shao-Fei, Wang, Rui, Li, Yan, Zuo, Jian, Han, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721667/
https://www.ncbi.nlm.nih.gov/pubmed/34987400
http://dx.doi.org/10.3389/fphar.2021.785586