Cargando…

Research progress on SLC7A11 in the regulation of cystine/cysteine metabolism in tumors

Solute carrier family 7 member 11 (SLC7A11) is a major transporter regulating cysteine metabolism and is widely expressed in a variety of tumor cells. SLC7A11 plays an important role in the occurrence, development, invasion and metastasis of tumors by regulating the transport of cysteine in the tumo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Xiang, Chen, Wei, Liu, Hui, Liu, Na, Chen, Deyu, Tian, Dalong, Wang, Jingzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721856/ https://www.ncbi.nlm.nih.gov/pubmed/34992680 http://dx.doi.org/10.3892/ol.2021.13165

Ejemplares similares

The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer
por: Jyotsana, Nidhi, et al.
Publicado: (2022)

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease
por: Vallerga, Costanza L., et al.
Publicado: (2020)

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
por: Koppula, Pranavi, et al.
Publicado: (2020)

Rotavirus-induced lncRNA SLC7A11-AS1 promotes ferroptosis by targeting cystine/glutamate antiporter xCT (SLC7A11) to facilitate virus infection
por: Banerjee, Shreya, et al.
Publicado: (2023)

Stress-induced inhibition of nonsense mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11
por: Martin, Leenus, et al.
Publicado: (2014)

Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
por: Lim, Jonathan K. M., et al.
Publicado: (2019)

Diagnosing Alzheimer’s Disease Specifically and Sensitively With pLG72 and Cystine/Glutamate Antiporter SLC7A11 AS Blood Biomarkers
por: Lane, Hsien-Yuan, et al.
Publicado: (2022)

Molecular cloning, tissue distribution and the expression of cystine/glutamate exchanger (xCT, SLC7A11) in different tissues during development in broiler chickens
por: Choi, Janghan, et al.
Publicado: (2020)

The antioxidant l-Ergothioneine prevents cystine lithiasis in the Slc7a9(−/−) mouse model of cystinuria
por: Mayayo-Vallverdú, Clara, et al.
Publicado: (2023)

NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation
por: Liu, Xiaoguang, et al.
Publicado: (2020)

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11
por: Mukhopadhyay, Subhadip, et al.
Publicado: (2021)

Genetic and Clinical Analyses of 13 Chinese Families With Cystine Urolithiasis and Identification of 15 Novel Pathogenic Variants in SLC3A1 and SLC7A9
por: Li, Chuangye, et al.
Publicado: (2020)

Activated human CD4(+) T cells express transporters for both cysteine and cystine
por: Levring, Trine Bøegh, et al.
Publicado: (2012)

Downregulation of lncRNA SLC7A11-AS1 decreased the NRF2/SLC7A11 expression and inhibited the progression of colorectal cancer cells
por: Wang, Tian, et al.
Publicado: (2023)

Plasma cysteine/cystine redox couple disruption in animal models of temporal lobe epilepsy
por: Liang, Li-Ping, et al.
Publicado: (2016)

Close correlation between thiolate basicity and certain NMR parameters in cysteine and cystine microspecies
por: Ferreira de Santana, Juliana, et al.
Publicado: (2022)

No evidence for point mutations in the novel renal cystine transporter AGT1/SLC7A13 contributing to the etiology of cystinuria
por: Olschok, Kathrin, et al.
Publicado: (2018)

Selenomethionine (Se-Met) Induces the Cystine/Glutamate Exchanger SLC7A11 in Cultured Human Retinal Pigment Epithelial (RPE) Cells: Implications for Antioxidant Therapy in Aging Retina
por: Ananth, Sudha, et al.
Publicado: (2020)

Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11
por: Zhang, Long, et al.
Publicado: (2022)

PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer
por: Shen, Liliang, et al.
Publicado: (2022)

Actinobacillus pleuropneumoniae FliY and YdjN are involved in cysteine/cystine utilization, oxidative resistance, and biofilm formation but are not determinants of virulence
por: Zhao, Fan, et al.
Publicado: (2023)

xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression
por: Ji, Xiangming, et al.
Publicado: (2018)

An l-cystine/l-cysteine impregnated nanofiltration membrane with the superior performance of an anchoring heavy metal in wastewater
por: Zhang, Hong-Li, et al.
Publicado: (2020)

Listeria monocytogenes TcyKLMN Cystine/Cysteine Transporter Facilitates Glutathione Synthesis and Virulence Gene Expression
por: Brenner, Moran, et al.
Publicado: (2022)

Cystine nephrolithiasis
por: Fattah, Hasan, et al.
Publicado: (2014)

Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target
por: Lohoff, Falk W., et al.
Publicado: (2021)

Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytes
por: Liu, Yifan, et al.
Publicado: (2023)

SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer
por: Lee, Jaewang, et al.
Publicado: (2022)

COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism
por: Feng, Yetong, et al.
Publicado: (2022)

Targeted demethylation of the SLC5A7 promotor inhibits colorectal cancer progression
por: Li, Yang, et al.
Publicado: (2022)

Substrate recognition and ATPase activity of the E. coli cysteine/cystine ABC transporter YecSC-FliY
por: Sabrialabed, Siwar, et al.
Publicado: (2020)

A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCT(KO) Pancreatic Ductal Adenocarcinoma Cells
por: Meira, Willian, et al.
Publicado: (2021)

SLC12A5 promotes hepatocellular carcinoma growth and ferroptosis resistance by inducing ER stress and cystine transport changes
por: Tong, Qing, et al.
Publicado: (2023)

Ferroptosis is involved in the progression of hepatocellular carcinoma through the circ0097009/miR-1261/SLC7A11 axis
por: Lyu, Ning, et al.
Publicado: (2021)

METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition
por: Bi, Fangfang, et al.
Publicado: (2023)

HSDL2 knockdown promotes the progression of cholangiocarcinoma by inhibiting ferroptosis through the P53/SLC7A11 axis
por: Ma, Shuoshuo, et al.
Publicado: (2023)

Cystinuria and Cystine Calculi
Publicado: (1930)

The sulfur formation system mediating extracellular cysteine‐cystine recycling in Fervidobacterium islandicum AW‐1 is associated with keratin degradation
por: Jin, Hyeon‐Su, et al.
Publicado: (2020)

The Role of SLC7A11 in Cancer: Friend or Foe?
por: Li, Sijia, et al.
Publicado: (2022)

Redox States of Protein Cysteines in Pathways of Protein Turnover and Cytoskeleton Dynamics Are Changed with Aging and Reversed by Slc7a11 Restoration in Mouse Lung Fibroblasts
por: Zheng, Yuxuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_83ab7jd9c1tto2e4o8nhg9mu6v