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Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave

INTRODUCTION: Asymptomatic COVID-19 patients are the most challenging and feared obstacles in resuming these surgical procedures. The purpose of this study was to evaluate the proportion of asymptomatic carriers detected by RT-PCR in pre-operative orthopaedic evaluation during the peak of the second...

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Autores principales: Samiul Islam, Md., Parvin, Sultana, Mahbubur Rahman Khan, Mohammad, Jahangir Hossain, G.M., Zahiruddin, A.K.M., Jahangir Alam, Md, Hossen, Monaim, Wahidur Rahman, Md, Shahidul Islam, Syed, Abdul Gani Mollah, Md
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of British Infection Association. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721921/
https://www.ncbi.nlm.nih.gov/pubmed/35005607
http://dx.doi.org/10.1016/j.clinpr.2021.100131
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author Samiul Islam, Md.
Parvin, Sultana
Mahbubur Rahman Khan, Mohammad
Jahangir Hossain, G.M.
Zahiruddin, A.K.M.
Jahangir Alam, Md
Hossen, Monaim
Wahidur Rahman, Md
Shahidul Islam, Syed
Abdul Gani Mollah, Md
author_facet Samiul Islam, Md.
Parvin, Sultana
Mahbubur Rahman Khan, Mohammad
Jahangir Hossain, G.M.
Zahiruddin, A.K.M.
Jahangir Alam, Md
Hossen, Monaim
Wahidur Rahman, Md
Shahidul Islam, Syed
Abdul Gani Mollah, Md
author_sort Samiul Islam, Md.
collection PubMed
description INTRODUCTION: Asymptomatic COVID-19 patients are the most challenging and feared obstacles in resuming these surgical procedures. The purpose of this study was to evaluate the proportion of asymptomatic carriers detected by RT-PCR in pre-operative orthopaedic evaluation during the peak of the second wave. METHODS: 514 asymptomtomatic COVID-19 patients, negative for TOCC (Travel, Profession, Cluster, Contact) risk factors were observed retrospectively. A nasopharyFngeal RT-PCR test was obtained 48 to 72 h before the surgery in all cases. Possible risk factors for a positive test was identified. RESULTS: The detected asymptomatic COVID-19 infection rate during the peak of the second wave among the pre-operative orthopaedic patients was 12.3%. Younger age, female gender, longer duration of admission to RT-PCR test interval were found to be significant (p= < 0.05) risk factors for asymptomatic RT-PCR to be positive. The hazard ratio (HR) for being asymptomatic RT-PCR positive was 4.3 (p = 0. 025), while the RT-PCR was performed at 14 days, but the HR increased to 9.2 (p = 0.049) when the test was performed after 45 days. CONCLUSION: According to our findings, pre-operative testing to rule out COVID-19 should be regarded as a critical step in preventing the disease clusters in hospitals.
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spelling pubmed-87219212022-01-03 Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave Samiul Islam, Md. Parvin, Sultana Mahbubur Rahman Khan, Mohammad Jahangir Hossain, G.M. Zahiruddin, A.K.M. Jahangir Alam, Md Hossen, Monaim Wahidur Rahman, Md Shahidul Islam, Syed Abdul Gani Mollah, Md Clin Infect Pract Article INTRODUCTION: Asymptomatic COVID-19 patients are the most challenging and feared obstacles in resuming these surgical procedures. The purpose of this study was to evaluate the proportion of asymptomatic carriers detected by RT-PCR in pre-operative orthopaedic evaluation during the peak of the second wave. METHODS: 514 asymptomtomatic COVID-19 patients, negative for TOCC (Travel, Profession, Cluster, Contact) risk factors were observed retrospectively. A nasopharyFngeal RT-PCR test was obtained 48 to 72 h before the surgery in all cases. Possible risk factors for a positive test was identified. RESULTS: The detected asymptomatic COVID-19 infection rate during the peak of the second wave among the pre-operative orthopaedic patients was 12.3%. Younger age, female gender, longer duration of admission to RT-PCR test interval were found to be significant (p= < 0.05) risk factors for asymptomatic RT-PCR to be positive. The hazard ratio (HR) for being asymptomatic RT-PCR positive was 4.3 (p = 0. 025), while the RT-PCR was performed at 14 days, but the HR increased to 9.2 (p = 0.049) when the test was performed after 45 days. CONCLUSION: According to our findings, pre-operative testing to rule out COVID-19 should be regarded as a critical step in preventing the disease clusters in hospitals. The Authors. Published by Elsevier Ltd on behalf of British Infection Association. 2022-01 2022-01-03 /pmc/articles/PMC8721921/ /pubmed/35005607 http://dx.doi.org/10.1016/j.clinpr.2021.100131 Text en © 2022 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Samiul Islam, Md.
Parvin, Sultana
Mahbubur Rahman Khan, Mohammad
Jahangir Hossain, G.M.
Zahiruddin, A.K.M.
Jahangir Alam, Md
Hossen, Monaim
Wahidur Rahman, Md
Shahidul Islam, Syed
Abdul Gani Mollah, Md
Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
title Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
title_full Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
title_fullStr Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
title_full_unstemmed Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
title_short Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
title_sort asymptomatic rt-pcr positive covid-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721921/
https://www.ncbi.nlm.nih.gov/pubmed/35005607
http://dx.doi.org/10.1016/j.clinpr.2021.100131
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