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Elevated SAA1 promotes the development of insulin resistance in ovarian granulosa cells in polycystic ovary syndrome
BACKGROUND: Insulin resistance (IR) contributes to ovarian dysfunctions in polycystic ovarian syndrome (PCOS) patients. Serum amyloid A1 (SAA1) is an acute phase protein produced primarily by the liver in response to inflammation. In addition to its role in inflammation, SAA1 may participate in IR d...
Autores principales: | Zhu, Qinling, Yao, Yue, Xu, Lizhen, Wu, Hasiximuke, Wang, Wangsheng, He, Yaqiong, Wang, Yuan, Lu, Yao, Qi, Jia, Ding, Ying, Li, Xinyu, Huang, Jiaan, Zhao, Hanting, Du, Yanzhi, Sun, Kang, Sun, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721971/ https://www.ncbi.nlm.nih.gov/pubmed/34980155 http://dx.doi.org/10.1186/s12958-021-00873-3 |
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