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Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling

Balance between the hematopoietic stem cell (HSC) duality to either possess self-renewal capacity or differentiate into multipotency progenitors (MPPs) is crucial for maintaining homeostasis of the hematopoietic stem/progenitor cell (HSPC) compartment. To retain the HSC self-renewal activity, KIT, a...

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Detalles Bibliográficos
Autores principales: Young, In-Chi, Wu, Bogang, Andricovich, Jaclyn, Chuang, Sung-Ting, Li, Rong, Tzatsos, Alexandros, Wu, Ray-Chang, Wu, Mei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722094/
https://www.ncbi.nlm.nih.gov/pubmed/34818550
http://dx.doi.org/10.1016/j.celrep.2021.110036