Cargando…

DL-3-n-butylphthalide promotes hippocampal neurogenesis and reduces mossy fiber sprouting in chronic temporal lobe epilepsy rats

BACKGROUND: A decrease in hippocampal neurogenesis is considered an important cause of cognitive impairment, while changes in mossy fiber sprouting are closely related to development of spontaneous recurrent seizures in chronic temporal lobe epilepsy (TLE). Racemic l-3-n-butylphthalide (DL-NBP) can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Shanshan, Liu, Fangxi, Shi, Wei, Wang, Jialu, Zhou, Zhike, Zhang, Xiaoqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722179/ https://www.ncbi.nlm.nih.gov/pubmed/34979964 http://dx.doi.org/10.1186/s12883-021-02516-x

Ejemplares similares

Astrocyte Role in Temporal Lobe Epilepsy and Development of Mossy Fiber Sprouting
por: Twible, Carolyn, et al.
Publicado: (2021)

One Seizure Please, Hold the Sprouts: The Role of Hippocampal Mossy Fiber Sprouting in Epilepsy
por: Beenhakker, Mark, et al.
Publicado: (2019)

Editorial: The Developmental Seizure-Induced Hippocampal Mossy Fiber Sprouting: Target for Epilepsy Therapies?
por: Ni, Hong, et al.
Publicado: (2019)

Is Mossy Fiber Sprouting a Potential Therapeutic Target for Epilepsy?
por: Cavarsan, Clarissa F., et al.
Publicado: (2018)

Signaling Pathways and Cellular Mechanisms Regulating Mossy Fiber Sprouting in the Development of Epilepsy
por: Godale, Christin M., et al.
Publicado: (2018)

TRPM4 regulates hilar mossy cell loss in temporal lobe epilepsy
por: Mundrucz, Laura, et al.
Publicado: (2023)

Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model
por: SONG, MING-YU, et al.
Publicado: (2015)

The Molecular and Cellular Mechanisms of Axon Guidance in Mossy Fiber Sprouting
por: Koyama, Ryuta, et al.
Publicado: (2018)

Detection of aberrant hippocampal mossy fiber connections: Ex vivo mesoscale diffusion MRI and microtractography with histological validation in a patient with uncontrolled temporal lobe epilepsy
por: Modo, Michel, et al.
Publicado: (2015)

Mixed neurotransmission in the hippocampal mossy fibers
por: Münster-Wandowski, Agnieszka, et al.
Publicado: (2013)

Pcdh11x controls target specification of mossy fiber sprouting
por: Luo, Wenshu, et al.
Publicado: (2022)

Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy
por: Arshad, Muhammad N., et al.
Publicado: (2022)

Adult Hippocampal Neurogenesis and Plasticity in the Infrapyramidal Bundle of the Mossy Fiber Projection: I. Co-Regulation by Activity
por: Römer, Benedikt, et al.
Publicado: (2011)

Reorganization of supramammillary–hippocampal pathways in the rat pilocarpine model of temporal lobe epilepsy: evidence for axon terminal sprouting
por: Soussi, Rabia, et al.
Publicado: (2014)

Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies
por: Asadi-Pooya, Ali A., et al.
Publicado: (2015)

E-I E-I Woe: Mossy Cell Regulation of Granule Cell Activity in Temporal Lobe Epilepsy
por: Goicouria, Luis, et al.
Publicado: (2020)

Electroacupuncture at ST36-ST37 and at Ear Ameliorates Hippocampal Mossy Fiber Sprouting in Kainic Acid-Induced Epileptic Seizure Rats
por: Liu, Chung-Hsiang, et al.
Publicado: (2014)

Multiple hippocampal transections for mesial temporal lobe epilepsy
por: Pitskhelauri, David, et al.
Publicado: (2021)

Altered adult neurogenesis and gliogenesis in mesial temporal lobe epilepsy patients
por: Ammothumkandy, Aswathy, et al.
Publicado: (2022)

Information processing and synaptic plasticity at hippocampal mossy fiber terminals
por: Evstratova, Alesya, et al.
Publicado: (2014)

Modeling Analysis of Axonal After Potential at Hippocampal Mossy Fibers
por: Kamiya, Haruyuki
Publicado: (2019)

Neuropilin-2 Signaling Modulates Mossy Fiber Sprouting by Regulating Axon Collateral Formation Through CRMP2 in a Rat Model of Epilepsy
por: Li, Yuxiang, et al.
Publicado: (2022)

The vulnerability of calretinin-containing hippocampal interneurons to temporal lobe epilepsy
por: Tóth, Kinga, et al.
Publicado: (2014)

Hippocampal subfield segmentation in temporal lobe epilepsy: Relation to outcomes
por: Kreilkamp, B. A. K., et al.
Publicado: (2018)

Clinical validation of automated hippocampal segmentation in temporal lobe epilepsy
por: Hadar, Peter N., et al.
Publicado: (2018)

Hippocampal Shape Is Associated with Memory Deficits in Temporal Lobe Epilepsy
por: Postma, Tjardo S., et al.
Publicado: (2020)

Mammillary Body Atrophy in Temporal Lobe Epilepsy With Hippocampal Sclerosis
por: Cho, Kyoo Ho, et al.
Publicado: (2022)

NeuroD2 regulates the development of hippocampal mossy fiber synapses
por: Wilke, Scott A, et al.
Publicado: (2012)

cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal
por: Shahoha, Meishar, et al.
Publicado: (2022)

Temporal lobe epilepsy alters spatio-temporal dynamics of the hippocampal functional network
por: Morgan, Victoria L., et al.
Publicado: (2020)

Adult Hippocampal Neurogenesis and Plasticity in the Infrapyramidal Bundle of the Mossy Fiber Projection: II. Genetic Covariation and Identification of Nos1 as Linking Candidate Gene
por: Krebs, Julia, et al.
Publicado: (2011)

The interplay of seizures-induced axonal sprouting and transcription-dependent Bdnf repositioning in the model of temporal lobe epilepsy
por: Skupien-Jaroszek, Anna, et al.
Publicado: (2021)

Protective effects of dl-3n-butylphthalide against diffuse brain injury
por: Zhao, Yaning, et al.
Publicado: (2013)

Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2019)

Synapsin- and Actin-Dependent Frequency Enhancement in Mouse Hippocampal Mossy Fiber Synapses
por: Owe, Simen G., et al.
Publicado: (2009)

Predominant Role of Serotonin at the Hippocampal Mossy Fiber Synapse with Redundant Monoaminergic Modulation
por: Kobayashi, Katsunori, et al.
Publicado: (2020)

Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses
por: Vandael, David, et al.
Publicado: (2021)

Modeling analysis of subthreshold voltage signaling along hippocampal mossy fiber axons
por: Kamiya, Haruyuki
Publicado: (2022)

Psychiatric Symptoms in Temporal Lobe Epilepsy with Left Mesial Hippocampal Sclerosis
por: Jang, Hyun, et al.
Publicado: (2015)

Hippocampal Pathophysiology: Commonality Shared by Temporal Lobe Epilepsy and Psychiatric Disorders
por: Nakahara, Soichiro, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5g1qqrb33e69tomvg7gotjlcvt