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DL-3-n-butylphthalide promotes hippocampal neurogenesis and reduces mossy fiber sprouting in chronic temporal lobe epilepsy rats

BACKGROUND: A decrease in hippocampal neurogenesis is considered an important cause of cognitive impairment, while changes in mossy fiber sprouting are closely related to development of spontaneous recurrent seizures in chronic temporal lobe epilepsy (TLE). Racemic l-3-n-butylphthalide (DL-NBP) can...

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Detalles Bibliográficos
Autores principales:	Zhao, Shanshan, Liu, Fangxi, Shi, Wei, Wang, Jialu, Zhou, Zhike, Zhang, Xiaoqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722179/ https://www.ncbi.nlm.nih.gov/pubmed/34979964 http://dx.doi.org/10.1186/s12883-021-02516-x

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