Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma

BACKGROUND: Drug resistance to sorafenib greatly limited the benefits of treatment in patients with hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) participate in the development of drug resistance. The key miRNA regulators related to the clinical outcome of sorafenib treatment and their molecula...

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Detalles Bibliográficos
Autores principales: Lu, Yuanjun, Chan, Yau-Tuen, Tan, Hor-Yue, Zhang, Cheng, Guo, Wei, Xu, Yu, Sharma, Rakesh, Chen, Zhe-Sheng, Zheng, Yi-Chao, Wang, Ning, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722264/
https://www.ncbi.nlm.nih.gov/pubmed/34980204
http://dx.doi.org/10.1186/s13046-021-02208-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722264/
https://www.ncbi.nlm.nih.gov/pubmed/34980204
http://dx.doi.org/10.1186/s13046-021-02208-x

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