CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma

BACKGROUND: Calcification of adamantinomatous craniopharyngioma (ACP) often causes problems with tumor resection, leading to a high incidence of deadly complications and tumor recurrence. Histone acetyltransferase (HAT) and histone deacetylase (HDAC) are 2 key enzymes that regulate histone acetylati...

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Detalles Bibliográficos
Autores principales: Yan, Xiaorong, Kang, Dezhi, Lin, Yuanxiang, Qi, Songtao, Jiang, Changzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722308/
https://www.ncbi.nlm.nih.gov/pubmed/34980138
http://dx.doi.org/10.1186/s12964-021-00797-w

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