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Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment

BACKGROUND: Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify treatment. Response-adaptive de-escalated treatment is promising, however improved biomarkers are needed. Quantitative cell-free HPV-DNA (cfHPV-DNA) in plas...

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Detalles Bibliográficos
Autores principales: Rosenberg, Ari J., Izumchenko, Evgeny, Pearson, Alexander, Gooi, Zhen, Blair, Elizabeth, Karrison, Theodore, Juloori, Aditya, Ginat, Daniel, Cipriani, Nicole, Lingen, Mark, Sloane, Hillary, Edelstein, Daniel L., Keyser, Kirsten, Fredebohm, Johannes, Holtrup, Frank, Jones, Frederick S., Haraf, Daniel, Agrawal, Nishant, Vokes, Everett E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722316/
https://www.ncbi.nlm.nih.gov/pubmed/34980038
http://dx.doi.org/10.1186/s12885-021-09146-z