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Increased Plasma Heparanase Activity and Endothelial Glycocalyx Degradation in Dengue Patients Is Associated With Plasma Leakage

BACKGROUND: Endothelial hyper-permeability with plasma leakage and thrombocytopenia are predominant features of severe dengue virus infection. It is well established that heparanase, the endothelial glycocalyx degrading enzyme, plays a major role in various diseases with vascular leakage. It is yet...

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Detalles Bibliográficos
Autores principales:	Buijsers, Baranca, Garishah, Fadel Muhammad, Riswari, Silvita Fitri, van Ast, Rosalie M., Pramudo, Setyo Gundi, Tunjungputri, Rahajeng N., Overheul, Gijs J., van Rij, Ronald P., van der Ven, André, Alisjahbana, Bachti, Gasem, Muhammad Hussein, de Mast, Quirijn, van der Vlag, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722520/ https://www.ncbi.nlm.nih.gov/pubmed/34987504 http://dx.doi.org/10.3389/fimmu.2021.759570

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