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Passenger Lymphocyte Syndrome after Renal Transplant: Case Report
Passenger lymphocyte syndrome (PLS) is a rare cause of anemia resulting from immune-mediated hemolysis in the post-transplant recipient. We report a case of 26-year-old male who underwent renal transplant. His mother as donor was O positive while he was A positive. He developed anemia at 1-week post...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722550/ https://www.ncbi.nlm.nih.gov/pubmed/35068769 http://dx.doi.org/10.4103/ijn.IJN_247_20 |
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author | Mandowara, Bhavin S. Mazumdar, Mehul R. Patel, Himanshu A. Darji, Prakash I. |
author_facet | Mandowara, Bhavin S. Mazumdar, Mehul R. Patel, Himanshu A. Darji, Prakash I. |
author_sort | Mandowara, Bhavin S. |
collection | PubMed |
description | Passenger lymphocyte syndrome (PLS) is a rare cause of anemia resulting from immune-mediated hemolysis in the post-transplant recipient. We report a case of 26-year-old male who underwent renal transplant. His mother as donor was O positive while he was A positive. He developed anemia at 1-week post-transplant, which later turned out to be PLS. Laboratory findings included rapidly decreasing Hb level and intravascular hemolysis. Hemolysis was brief, because the lymphocytes passed on with the donor organ were able to proliferate only for a while. The case signifies the importance of PLS as a cause for anemia, specifically in the early period after solid organ transplant. It is usually self-limiting, and the treatment requires blood transfusion of donor's blood group. |
format | Online Article Text |
id | pubmed-8722550 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-87225502022-01-20 Passenger Lymphocyte Syndrome after Renal Transplant: Case Report Mandowara, Bhavin S. Mazumdar, Mehul R. Patel, Himanshu A. Darji, Prakash I. Indian J Nephrol Case Report Passenger lymphocyte syndrome (PLS) is a rare cause of anemia resulting from immune-mediated hemolysis in the post-transplant recipient. We report a case of 26-year-old male who underwent renal transplant. His mother as donor was O positive while he was A positive. He developed anemia at 1-week post-transplant, which later turned out to be PLS. Laboratory findings included rapidly decreasing Hb level and intravascular hemolysis. Hemolysis was brief, because the lymphocytes passed on with the donor organ were able to proliferate only for a while. The case signifies the importance of PLS as a cause for anemia, specifically in the early period after solid organ transplant. It is usually self-limiting, and the treatment requires blood transfusion of donor's blood group. Wolters Kluwer - Medknow 2021 2021-02-16 /pmc/articles/PMC8722550/ /pubmed/35068769 http://dx.doi.org/10.4103/ijn.IJN_247_20 Text en Copyright: © 2021 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Mandowara, Bhavin S. Mazumdar, Mehul R. Patel, Himanshu A. Darji, Prakash I. Passenger Lymphocyte Syndrome after Renal Transplant: Case Report |
title | Passenger Lymphocyte Syndrome after Renal Transplant: Case Report |
title_full | Passenger Lymphocyte Syndrome after Renal Transplant: Case Report |
title_fullStr | Passenger Lymphocyte Syndrome after Renal Transplant: Case Report |
title_full_unstemmed | Passenger Lymphocyte Syndrome after Renal Transplant: Case Report |
title_short | Passenger Lymphocyte Syndrome after Renal Transplant: Case Report |
title_sort | passenger lymphocyte syndrome after renal transplant: case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722550/ https://www.ncbi.nlm.nih.gov/pubmed/35068769 http://dx.doi.org/10.4103/ijn.IJN_247_20 |
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