Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient

Acute Kidney Injury (AKI) in COVID-19 patients is common and independently associated with higher mortality. The pathophysiology of AKI is multifactorial and may be either direct viral trophism or immune mediated injury and hypercoagulability. This case highlights AKI in a young female with severe C...

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Autores principales: Kulkarni, Amitabh, Nasa, Prashant, Polumuru, Srinivasa, Singh, Aanchal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722555/
https://www.ncbi.nlm.nih.gov/pubmed/35068764
http://dx.doi.org/10.4103/ijn.IJN_374_20
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author Kulkarni, Amitabh
Nasa, Prashant
Polumuru, Srinivasa
Singh, Aanchal
author_facet Kulkarni, Amitabh
Nasa, Prashant
Polumuru, Srinivasa
Singh, Aanchal
author_sort Kulkarni, Amitabh
collection PubMed
description Acute Kidney Injury (AKI) in COVID-19 patients is common and independently associated with higher mortality. The pathophysiology of AKI is multifactorial and may be either direct viral trophism or immune mediated injury and hypercoagulability. This case highlights AKI in a young female with severe COVID-19 due to complement-3 mediated thrombotic microangiopathy with pre-existing chronic kidney disease likely because of IgA nephropathy.
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spelling pubmed-87225552022-01-20 Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient Kulkarni, Amitabh Nasa, Prashant Polumuru, Srinivasa Singh, Aanchal Indian J Nephrol Case Report Acute Kidney Injury (AKI) in COVID-19 patients is common and independently associated with higher mortality. The pathophysiology of AKI is multifactorial and may be either direct viral trophism or immune mediated injury and hypercoagulability. This case highlights AKI in a young female with severe COVID-19 due to complement-3 mediated thrombotic microangiopathy with pre-existing chronic kidney disease likely because of IgA nephropathy. Wolters Kluwer - Medknow 2021 2021-03-27 /pmc/articles/PMC8722555/ /pubmed/35068764 http://dx.doi.org/10.4103/ijn.IJN_374_20 Text en Copyright: © 2021 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kulkarni, Amitabh
Nasa, Prashant
Polumuru, Srinivasa
Singh, Aanchal
Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
title Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
title_full Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
title_fullStr Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
title_full_unstemmed Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
title_short Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
title_sort thrombotic microangiopathy causing acute kidney injury in a covid-19 patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722555/
https://www.ncbi.nlm.nih.gov/pubmed/35068764
http://dx.doi.org/10.4103/ijn.IJN_374_20
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