Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma

BACKGROUND: The efficacy of polyclonal high titer convalescent plasma to prevent serious complications of COVID-19 in outpatients with recent onset of illness is uncertain. METHODS: This multicenter, double-blind randomized controlled trial compared the efficacy and safety of SARS-CoV-2 high titer c...

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Detalles Bibliográficos
Autores principales: Sullivan, David J., Gebo, Kelly A., Shoham, Shmuel, Bloch, Evan M., Lau, Bryan, Shenoy, Aarthi G., Mosnaim, Giselle S., Gniadek, Thomas J., Fukuta, Yuriko, Patel, Bela, Heath, Sonya L., Levine, Adam C., Meisenberg, Barry R., Spivak, Emily S., Anjan, Shweta, Huaman, Moises A., Blair, Janis E., Currier, Judith S., Paxton, James H., Gerber, Jonathan M., Petrini, Joann R., Broderick, Patrick B., Rausch, William, Cordisco, Marie Elena, Hammel, Jean, Greenblatt, Benjamin, Cluzet, Valerie C., Cruser, Daniel, Oei, Kevin, Abinante, Matthew, Hammitt, Laura L., Sutcliffe, Catherine G., Forthal, Donald N., Zand, Martin S., Cachay, Edward R., Raval, Jay S., Kassaye, Seble G., Foster, E. Colin, Roth, Michael, Marshall, Christi E., Yarava, Anusha, Lane, Karen, McBee, Nichol A., Gawad, Amy L., Karlen, Nicky, Singh, Atika, Ford, Daniel E., Jabs, Douglas A., Appel, Lawrence J., Shade, David M., Ehrhardt, Stephan, Baksh, Sheriza N., Laeyendecker, Oliver, Pekosz, Andrew, Klein, Sabra L., Casadevall, Arturo, Tobian, Aaron A.R., Hanley, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722611/
https://www.ncbi.nlm.nih.gov/pubmed/34981068
http://dx.doi.org/10.1101/2021.12.10.21267485

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