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Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables

This work proposes an explainable artificial intelligence approach to help diagnose COVID-19 patients based on blood test and pathogen variables. Two glass-box models, logistic regression and explainable boosting machine, and two black-box models, random forest and support vector machine, were used...

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Detalles Bibliográficos
Autores principales: Thimoteo, Lucas M., Vellasco, Marley M., Amaral, Jorge, Figueiredo, Karla, Yokoyama, Cátia Lie, Marques, Erito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722647/
http://dx.doi.org/10.1007/s40313-021-00858-y
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author Thimoteo, Lucas M.
Vellasco, Marley M.
Amaral, Jorge
Figueiredo, Karla
Yokoyama, Cátia Lie
Marques, Erito
author_facet Thimoteo, Lucas M.
Vellasco, Marley M.
Amaral, Jorge
Figueiredo, Karla
Yokoyama, Cátia Lie
Marques, Erito
author_sort Thimoteo, Lucas M.
collection PubMed
description This work proposes an explainable artificial intelligence approach to help diagnose COVID-19 patients based on blood test and pathogen variables. Two glass-box models, logistic regression and explainable boosting machine, and two black-box models, random forest and support vector machine, were used to assess the disease diagnosis. Shapley additive explanations were used to explain predictions for the black-box models, while glass-box models feature importance brought insights into the most relevant features. All global explanations show the eosinophils and leukocytes, white blood cells are among the essential features to help diagnose the COVID-19. Moreover, the best model obtained an AUC of 0.87.
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spelling pubmed-87226472022-01-04 Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables Thimoteo, Lucas M. Vellasco, Marley M. Amaral, Jorge Figueiredo, Karla Yokoyama, Cátia Lie Marques, Erito J Control Autom Electr Syst Article This work proposes an explainable artificial intelligence approach to help diagnose COVID-19 patients based on blood test and pathogen variables. Two glass-box models, logistic regression and explainable boosting machine, and two black-box models, random forest and support vector machine, were used to assess the disease diagnosis. Shapley additive explanations were used to explain predictions for the black-box models, while glass-box models feature importance brought insights into the most relevant features. All global explanations show the eosinophils and leukocytes, white blood cells are among the essential features to help diagnose the COVID-19. Moreover, the best model obtained an AUC of 0.87. Springer US 2022-01-03 2022 /pmc/articles/PMC8722647/ http://dx.doi.org/10.1007/s40313-021-00858-y Text en © Brazilian Society for Automatics--SBA 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Thimoteo, Lucas M.
Vellasco, Marley M.
Amaral, Jorge
Figueiredo, Karla
Yokoyama, Cátia Lie
Marques, Erito
Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
title Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
title_full Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
title_fullStr Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
title_full_unstemmed Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
title_short Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
title_sort explainable artificial intelligence for covid-19 diagnosis through blood test variables
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722647/
http://dx.doi.org/10.1007/s40313-021-00858-y
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