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Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma

BACKGROUND: Recent data propose a diagnostic and prognostic capacity for citrullinated histone H3 (H3Cit), a marker of neutrophil extracellular traps (NETs), in pathologic conditions such as cancer and thrombosis. However, current research is hampered by lack of standardized assays. OBJECTIVES: We a...

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Detalles Bibliográficos
Autores principales:	Thålin, Charlotte, Aguilera, Katherina, Hall, Nathan W., Marunde, Matthew R., Burg, Jonathan M., Rosell, Axel, Daleskog, Maud, Månsson, Maja, Hisada, Yohei, Meiners, Matthew J., Sun, Zu-Wen, Whelihan, Matthew F., Cheek, Marcus A., Howard, Sarah A., Saxena-Beem, Shruti, Noubouossie, Denis F., Key, Nigel S., Sheikh, Saira Z., Keogh, Michael-Christopher, Cowles, Martis W., Lundström, Staffan, Mackman, Nigel, Wallén, Håkan, Johnstone, Andrea L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722705/ https://www.ncbi.nlm.nih.gov/pubmed/32654410 http://dx.doi.org/10.1111/jth.15003

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