The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease

The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed over five million people worldwide as of December 2021 with infections rising again due to the emergence of highly transmissible variants. Animal models that faithfully recapitulate human disease are critical for a...

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Detalles Bibliográficos
Autores principales: Melton, Alexandra, Doyle-Meyers, Lara A., Blair, Robert V., Midkiff, Cecily, Melton, Hunter J., Russell-Lodrigue, Kasi, Aye, Pyone P., Schiro, Faith, Fahlberg, Marissa, Szeltner, Dawn, Spencer, Skye, Beddingfield, Brandon J., Goff, Kelly, Golden, Nadia, Penney, Toni, Picou, Breanna, Hensley, Krystle, Chandler, Kristin E., Plante, Jessica A., Plante, Kenneth S., Weaver, Scott C., Roy, Chad J., Hoxie, James A., Gao, Hongmei, Montefiori, David C., Mankowski, Joseph L., Bohm, Rudolf P., Rappaport, Jay, Maness, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722729/
https://www.ncbi.nlm.nih.gov/pubmed/34929014
http://dx.doi.org/10.1371/journal.ppat.1010162

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