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Sildenafil protects against pulmonary hypertension induced by hypoxia in neonatal rats via activation of PPARγ-mediated downregulation of TRPC

Persistent pulmonary hypertension of the newborn (PPHN) is a common pulmonary vascular disease during the neonatal period, and it is associated with a high clinical mortality rate and a poor prognosis. At present, the treatment of PPHN is based mainly on inhaled nitric oxide (iNO), high-frequency ve...

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Detalles Bibliográficos
Autores principales:	Huang, Wanjie, Liu, Na, Tong, Xin, Du, Yanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722768/ https://www.ncbi.nlm.nih.gov/pubmed/34935055 http://dx.doi.org/10.3892/ijmm.2021.5074

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