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UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data

SUMMARY: UCSC Xena platform provides huge amounts of processed cancer omics data from large cancer research projects (e.g. TCGA, CCLE and PCAWG) or individual research groups and enables unprecedented research opportunities. However, a graphical user interface-based tool for interactively analyzing...

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Detalles Bibliográficos
Autores principales: Wang, Shixiang, Xiong, Yi, Zhao, Longfei, Gu, Kai, Li, Yin, Zhao, Fei, Li, Jianfeng, Wang, Mingjie, Wang, Haitao, Tao, Ziyu, Wu, Tao, Zheng, Yichao, Li, Xuejun, Liu, Xue-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723150/
https://www.ncbi.nlm.nih.gov/pubmed/34323947
http://dx.doi.org/10.1093/bioinformatics/btab561
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author Wang, Shixiang
Xiong, Yi
Zhao, Longfei
Gu, Kai
Li, Yin
Zhao, Fei
Li, Jianfeng
Wang, Mingjie
Wang, Haitao
Tao, Ziyu
Wu, Tao
Zheng, Yichao
Li, Xuejun
Liu, Xue-Song
author_facet Wang, Shixiang
Xiong, Yi
Zhao, Longfei
Gu, Kai
Li, Yin
Zhao, Fei
Li, Jianfeng
Wang, Mingjie
Wang, Haitao
Tao, Ziyu
Wu, Tao
Zheng, Yichao
Li, Xuejun
Liu, Xue-Song
author_sort Wang, Shixiang
collection PubMed
description SUMMARY: UCSC Xena platform provides huge amounts of processed cancer omics data from large cancer research projects (e.g. TCGA, CCLE and PCAWG) or individual research groups and enables unprecedented research opportunities. However, a graphical user interface-based tool for interactively analyzing UCSC Xena data and generating elegant plots is still lacking, especially for cancer researchers and clinicians with limited programming experience. Here, we present UCSCXenaShiny, an R Shiny package for quickly searching, downloading, exploring, analyzing and visualizing data from UCSC Xena data hubs. This tool could effectively promote the practical use of public data, and can serve as an important complement to the current Xena genomics explorer. AVAILABILITY AND IMPLEMENTATION: UCSCXenaShiny is an open source R package under GPLv3 license and it is freely available at https://github.com/openbiox/UCSCXenaShiny or https://cran.r-project.org/package=UCSCXenaShiny. The docker image is available at https://hub.docker.com/r/shixiangwang/ucscxenashiny. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-87231502022-01-05 UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data Wang, Shixiang Xiong, Yi Zhao, Longfei Gu, Kai Li, Yin Zhao, Fei Li, Jianfeng Wang, Mingjie Wang, Haitao Tao, Ziyu Wu, Tao Zheng, Yichao Li, Xuejun Liu, Xue-Song Bioinformatics Applications Notes SUMMARY: UCSC Xena platform provides huge amounts of processed cancer omics data from large cancer research projects (e.g. TCGA, CCLE and PCAWG) or individual research groups and enables unprecedented research opportunities. However, a graphical user interface-based tool for interactively analyzing UCSC Xena data and generating elegant plots is still lacking, especially for cancer researchers and clinicians with limited programming experience. Here, we present UCSCXenaShiny, an R Shiny package for quickly searching, downloading, exploring, analyzing and visualizing data from UCSC Xena data hubs. This tool could effectively promote the practical use of public data, and can serve as an important complement to the current Xena genomics explorer. AVAILABILITY AND IMPLEMENTATION: UCSCXenaShiny is an open source R package under GPLv3 license and it is freely available at https://github.com/openbiox/UCSCXenaShiny or https://cran.r-project.org/package=UCSCXenaShiny. The docker image is available at https://hub.docker.com/r/shixiangwang/ucscxenashiny. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2021-07-29 /pmc/articles/PMC8723150/ /pubmed/34323947 http://dx.doi.org/10.1093/bioinformatics/btab561 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Wang, Shixiang
Xiong, Yi
Zhao, Longfei
Gu, Kai
Li, Yin
Zhao, Fei
Li, Jianfeng
Wang, Mingjie
Wang, Haitao
Tao, Ziyu
Wu, Tao
Zheng, Yichao
Li, Xuejun
Liu, Xue-Song
UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
title UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
title_full UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
title_fullStr UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
title_full_unstemmed UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
title_short UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
title_sort ucscxenashiny: an r/cran package for interactive analysis of ucsc xena data
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723150/
https://www.ncbi.nlm.nih.gov/pubmed/34323947
http://dx.doi.org/10.1093/bioinformatics/btab561
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