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High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India

Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal...

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Autores principales: Mahapatra, Bikash Ranjan, Barik, Bijay K, Muraleedharan, Anupam, Badajena, Avinash, Amritt, Adhar, Kanungo, Satyabrata, Pattanaik, Ashutosh, Mishra, Minakshi, Dhar, Sovan S, Barik, Sandip K, Das Majumdar, Saroj Kumar, Parida, Dillip Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723729/
https://www.ncbi.nlm.nih.gov/pubmed/35003939
http://dx.doi.org/10.7759/cureus.20063
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author Mahapatra, Bikash Ranjan
Barik, Bijay K
Muraleedharan, Anupam
Badajena, Avinash
Amritt, Adhar
Kanungo, Satyabrata
Pattanaik, Ashutosh
Mishra, Minakshi
Dhar, Sovan S
Barik, Sandip K
Das Majumdar, Saroj Kumar
Parida, Dillip Kumar
author_facet Mahapatra, Bikash Ranjan
Barik, Bijay K
Muraleedharan, Anupam
Badajena, Avinash
Amritt, Adhar
Kanungo, Satyabrata
Pattanaik, Ashutosh
Mishra, Minakshi
Dhar, Sovan S
Barik, Sandip K
Das Majumdar, Saroj Kumar
Parida, Dillip Kumar
author_sort Mahapatra, Bikash Ranjan
collection PubMed
description Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal anaesthesia to all patients. This study attempts dosimetric comparison of high-dose-rate ICBT with spinal anaesthesia to that under conscious sedation to find out whether brachytherapy under conscious sedation is comparable with spinal anaesthesia. Methods Retrospective data of total of 56 cervical cancer patients who received ICBT after completion of external beam radiotherapy (EBRT) were collected. Among these 56 patients, 28 patients received brachytherapy under spinal anaesthesia (SA group) and the rest under conscious sedation (CS group). Brachytherapy dose was 7 Gray per fraction weekly for three weeks. Thus, 84 brachytherapy plans of each group were analysed with respect to doses received by points A, B, P and Organs at Risk. Results The mean doses received by points A, B and P were comparable in SA and CS groups (p-value >0.05). Similarly, the mean doses received by Organs at Risk (rectum, urinary bladder, and sigmoid colon) were also comparable in both the groups (p-value>0.05). Conclusion ICBT under CS is dosimetrically non-inferior to SA, which makes it an alternative option.
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spelling pubmed-87237292022-01-06 High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India Mahapatra, Bikash Ranjan Barik, Bijay K Muraleedharan, Anupam Badajena, Avinash Amritt, Adhar Kanungo, Satyabrata Pattanaik, Ashutosh Mishra, Minakshi Dhar, Sovan S Barik, Sandip K Das Majumdar, Saroj Kumar Parida, Dillip Kumar Cureus Medical Physics Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal anaesthesia to all patients. This study attempts dosimetric comparison of high-dose-rate ICBT with spinal anaesthesia to that under conscious sedation to find out whether brachytherapy under conscious sedation is comparable with spinal anaesthesia. Methods Retrospective data of total of 56 cervical cancer patients who received ICBT after completion of external beam radiotherapy (EBRT) were collected. Among these 56 patients, 28 patients received brachytherapy under spinal anaesthesia (SA group) and the rest under conscious sedation (CS group). Brachytherapy dose was 7 Gray per fraction weekly for three weeks. Thus, 84 brachytherapy plans of each group were analysed with respect to doses received by points A, B, P and Organs at Risk. Results The mean doses received by points A, B and P were comparable in SA and CS groups (p-value >0.05). Similarly, the mean doses received by Organs at Risk (rectum, urinary bladder, and sigmoid colon) were also comparable in both the groups (p-value>0.05). Conclusion ICBT under CS is dosimetrically non-inferior to SA, which makes it an alternative option. Cureus 2021-11-30 /pmc/articles/PMC8723729/ /pubmed/35003939 http://dx.doi.org/10.7759/cureus.20063 Text en Copyright © 2021, Mahapatra et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Physics
Mahapatra, Bikash Ranjan
Barik, Bijay K
Muraleedharan, Anupam
Badajena, Avinash
Amritt, Adhar
Kanungo, Satyabrata
Pattanaik, Ashutosh
Mishra, Minakshi
Dhar, Sovan S
Barik, Sandip K
Das Majumdar, Saroj Kumar
Parida, Dillip Kumar
High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
title High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
title_full High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
title_fullStr High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
title_full_unstemmed High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
title_short High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
title_sort high-dose-rate intracavitary brachytherapy under conscious sedation a viable practical alternative to spinal anaesthesia in carcinoma cervix: a retrospective study in a tertiary care centre in eastern india
topic Medical Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723729/
https://www.ncbi.nlm.nih.gov/pubmed/35003939
http://dx.doi.org/10.7759/cureus.20063
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