Cargando…
High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India
Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723729/ https://www.ncbi.nlm.nih.gov/pubmed/35003939 http://dx.doi.org/10.7759/cureus.20063 |
_version_ | 1784625780957904896 |
---|---|
author | Mahapatra, Bikash Ranjan Barik, Bijay K Muraleedharan, Anupam Badajena, Avinash Amritt, Adhar Kanungo, Satyabrata Pattanaik, Ashutosh Mishra, Minakshi Dhar, Sovan S Barik, Sandip K Das Majumdar, Saroj Kumar Parida, Dillip Kumar |
author_facet | Mahapatra, Bikash Ranjan Barik, Bijay K Muraleedharan, Anupam Badajena, Avinash Amritt, Adhar Kanungo, Satyabrata Pattanaik, Ashutosh Mishra, Minakshi Dhar, Sovan S Barik, Sandip K Das Majumdar, Saroj Kumar Parida, Dillip Kumar |
author_sort | Mahapatra, Bikash Ranjan |
collection | PubMed |
description | Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal anaesthesia to all patients. This study attempts dosimetric comparison of high-dose-rate ICBT with spinal anaesthesia to that under conscious sedation to find out whether brachytherapy under conscious sedation is comparable with spinal anaesthesia. Methods Retrospective data of total of 56 cervical cancer patients who received ICBT after completion of external beam radiotherapy (EBRT) were collected. Among these 56 patients, 28 patients received brachytherapy under spinal anaesthesia (SA group) and the rest under conscious sedation (CS group). Brachytherapy dose was 7 Gray per fraction weekly for three weeks. Thus, 84 brachytherapy plans of each group were analysed with respect to doses received by points A, B, P and Organs at Risk. Results The mean doses received by points A, B and P were comparable in SA and CS groups (p-value >0.05). Similarly, the mean doses received by Organs at Risk (rectum, urinary bladder, and sigmoid colon) were also comparable in both the groups (p-value>0.05). Conclusion ICBT under CS is dosimetrically non-inferior to SA, which makes it an alternative option. |
format | Online Article Text |
id | pubmed-8723729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-87237292022-01-06 High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India Mahapatra, Bikash Ranjan Barik, Bijay K Muraleedharan, Anupam Badajena, Avinash Amritt, Adhar Kanungo, Satyabrata Pattanaik, Ashutosh Mishra, Minakshi Dhar, Sovan S Barik, Sandip K Das Majumdar, Saroj Kumar Parida, Dillip Kumar Cureus Medical Physics Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal anaesthesia to all patients. This study attempts dosimetric comparison of high-dose-rate ICBT with spinal anaesthesia to that under conscious sedation to find out whether brachytherapy under conscious sedation is comparable with spinal anaesthesia. Methods Retrospective data of total of 56 cervical cancer patients who received ICBT after completion of external beam radiotherapy (EBRT) were collected. Among these 56 patients, 28 patients received brachytherapy under spinal anaesthesia (SA group) and the rest under conscious sedation (CS group). Brachytherapy dose was 7 Gray per fraction weekly for three weeks. Thus, 84 brachytherapy plans of each group were analysed with respect to doses received by points A, B, P and Organs at Risk. Results The mean doses received by points A, B and P were comparable in SA and CS groups (p-value >0.05). Similarly, the mean doses received by Organs at Risk (rectum, urinary bladder, and sigmoid colon) were also comparable in both the groups (p-value>0.05). Conclusion ICBT under CS is dosimetrically non-inferior to SA, which makes it an alternative option. Cureus 2021-11-30 /pmc/articles/PMC8723729/ /pubmed/35003939 http://dx.doi.org/10.7759/cureus.20063 Text en Copyright © 2021, Mahapatra et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Medical Physics Mahapatra, Bikash Ranjan Barik, Bijay K Muraleedharan, Anupam Badajena, Avinash Amritt, Adhar Kanungo, Satyabrata Pattanaik, Ashutosh Mishra, Minakshi Dhar, Sovan S Barik, Sandip K Das Majumdar, Saroj Kumar Parida, Dillip Kumar High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India |
title | High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India |
title_full | High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India |
title_fullStr | High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India |
title_full_unstemmed | High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India |
title_short | High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India |
title_sort | high-dose-rate intracavitary brachytherapy under conscious sedation a viable practical alternative to spinal anaesthesia in carcinoma cervix: a retrospective study in a tertiary care centre in eastern india |
topic | Medical Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723729/ https://www.ncbi.nlm.nih.gov/pubmed/35003939 http://dx.doi.org/10.7759/cureus.20063 |
work_keys_str_mv | AT mahapatrabikashranjan highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT barikbijayk highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT muraleedharananupam highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT badajenaavinash highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT amrittadhar highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT kanungosatyabrata highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT pattanaikashutosh highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT mishraminakshi highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT dharsovans highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT bariksandipk highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT dasmajumdarsarojkumar highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia AT paridadillipkumar highdoserateintracavitarybrachytherapyunderconscioussedationaviablepracticalalternativetospinalanaesthesiaincarcinomacervixaretrospectivestudyinatertiarycarecentreineasternindia |