Cargando…

A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient

Central retinal artery occlusion (CRAO) is a multifactorial disease, where inflammation and hypercoagulability are the major risk factors. It is a rare occurrence in this geographical area in patients diagnosed with sinus mucormycosis infection, which has emerged as one of the most fulminant, opport...

Descripción completa

Detalles Bibliográficos
Autores principales: Patnaik, Abhishek, Sharma, Bharti, Ahmad, Reyaz, Kumar, Abhijit, Chitrotpala, Riti, Gupta, Minakshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723730/
https://www.ncbi.nlm.nih.gov/pubmed/35003938
http://dx.doi.org/10.7759/cureus.20062
_version_ 1784625781199077376
author Patnaik, Abhishek
Sharma, Bharti
Ahmad, Reyaz
Kumar, Abhijit
Chitrotpala, Riti
Gupta, Minakshi
author_facet Patnaik, Abhishek
Sharma, Bharti
Ahmad, Reyaz
Kumar, Abhijit
Chitrotpala, Riti
Gupta, Minakshi
author_sort Patnaik, Abhishek
collection PubMed
description Central retinal artery occlusion (CRAO) is a multifactorial disease, where inflammation and hypercoagulability are the major risk factors. It is a rare occurrence in this geographical area in patients diagnosed with sinus mucormycosis infection, which has emerged as one of the most fulminant, opportunistic secondary infection during post-COVID era. We report a case of a bilateral CRAO, in a 66-year-old, post-COVID, diabetic patient. A complete eye examination followed by radiological imaging of brain, orbit, and paranasal sinuses were done. Multidisciplinary approach was contemplated to reach a diagnosis of bilateral rhino-orbital-cerebral mucormycosis (ROCM). Intravenous liposomal amphotericin-B injection was started as a part of systemic management and an aggressive sinus debridement of both sides with amphotericin-B wash was also done. Despite an early diagnosis and intervention, the patient succumbed to her illness. All post-COVID patients presenting with the complaints of blurring of vision should be meticulously examined for the presence of any retinal abnormality in both the eyes as this may be a manifestation of an underlying secondary fungal infection. Early diagnosis of ROCM and management will help in reducing complications.
format Online
Article
Text
id pubmed-8723730
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-87237302022-01-06 A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient Patnaik, Abhishek Sharma, Bharti Ahmad, Reyaz Kumar, Abhijit Chitrotpala, Riti Gupta, Minakshi Cureus Ophthalmology Central retinal artery occlusion (CRAO) is a multifactorial disease, where inflammation and hypercoagulability are the major risk factors. It is a rare occurrence in this geographical area in patients diagnosed with sinus mucormycosis infection, which has emerged as one of the most fulminant, opportunistic secondary infection during post-COVID era. We report a case of a bilateral CRAO, in a 66-year-old, post-COVID, diabetic patient. A complete eye examination followed by radiological imaging of brain, orbit, and paranasal sinuses were done. Multidisciplinary approach was contemplated to reach a diagnosis of bilateral rhino-orbital-cerebral mucormycosis (ROCM). Intravenous liposomal amphotericin-B injection was started as a part of systemic management and an aggressive sinus debridement of both sides with amphotericin-B wash was also done. Despite an early diagnosis and intervention, the patient succumbed to her illness. All post-COVID patients presenting with the complaints of blurring of vision should be meticulously examined for the presence of any retinal abnormality in both the eyes as this may be a manifestation of an underlying secondary fungal infection. Early diagnosis of ROCM and management will help in reducing complications. Cureus 2021-11-30 /pmc/articles/PMC8723730/ /pubmed/35003938 http://dx.doi.org/10.7759/cureus.20062 Text en Copyright © 2021, Patnaik et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Patnaik, Abhishek
Sharma, Bharti
Ahmad, Reyaz
Kumar, Abhijit
Chitrotpala, Riti
Gupta, Minakshi
A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient
title A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient
title_full A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient
title_fullStr A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient
title_full_unstemmed A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient
title_short A Case of Bilateral Central Retinal Artery Occlusion in a Post-COVID Rhino-Orbital-Cerebral Mucormycosis Patient
title_sort case of bilateral central retinal artery occlusion in a post-covid rhino-orbital-cerebral mucormycosis patient
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723730/
https://www.ncbi.nlm.nih.gov/pubmed/35003938
http://dx.doi.org/10.7759/cureus.20062
work_keys_str_mv AT patnaikabhishek acaseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT sharmabharti acaseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT ahmadreyaz acaseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT kumarabhijit acaseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT chitrotpalariti acaseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT guptaminakshi acaseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT patnaikabhishek caseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT sharmabharti caseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT ahmadreyaz caseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT kumarabhijit caseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT chitrotpalariti caseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient
AT guptaminakshi caseofbilateralcentralretinalarteryocclusioninapostcovidrhinoorbitalcerebralmucormycosispatient