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Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment

Symptomatic iron overload and hyperferritinemia are rarely mentioned as complications of chronic hepatitis B infection. We report a case of a 70-year-old woman who presented with symptoms of iron overload including aches in the calves, fatigue, poor appetite, and low mood. Laboratory results showed...

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Detalles Bibliográficos
Autores principales: Tey, Tze Tong, Yiu, Richard, Leow, Wei Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723841/
https://www.ncbi.nlm.nih.gov/pubmed/34987872
http://dx.doi.org/10.1155/2021/8407257
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author Tey, Tze Tong
Yiu, Richard
Leow, Wei Qiang
author_facet Tey, Tze Tong
Yiu, Richard
Leow, Wei Qiang
author_sort Tey, Tze Tong
collection PubMed
description Symptomatic iron overload and hyperferritinemia are rarely mentioned as complications of chronic hepatitis B infection. We report a case of a 70-year-old woman who presented with symptoms of iron overload including aches in the calves, fatigue, poor appetite, and low mood. Laboratory results showed a serum ferritin of 2449 μg/L and transferrin saturation of 74%. Her symptoms completely resolved with hepatitis B antiviral treatment. Serum ferritin and transferrin saturation also normalized. Symptomatic iron overload is a rare yet clinically important complication that can result from chronic hepatitis B infection.
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spelling pubmed-87238412022-01-04 Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment Tey, Tze Tong Yiu, Richard Leow, Wei Qiang Case Rep Gastrointest Med Case Report Symptomatic iron overload and hyperferritinemia are rarely mentioned as complications of chronic hepatitis B infection. We report a case of a 70-year-old woman who presented with symptoms of iron overload including aches in the calves, fatigue, poor appetite, and low mood. Laboratory results showed a serum ferritin of 2449 μg/L and transferrin saturation of 74%. Her symptoms completely resolved with hepatitis B antiviral treatment. Serum ferritin and transferrin saturation also normalized. Symptomatic iron overload is a rare yet clinically important complication that can result from chronic hepatitis B infection. Hindawi 2021-12-27 /pmc/articles/PMC8723841/ /pubmed/34987872 http://dx.doi.org/10.1155/2021/8407257 Text en Copyright © 2021 Tze Tong Tey et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tey, Tze Tong
Yiu, Richard
Leow, Wei Qiang
Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment
title Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment
title_full Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment
title_fullStr Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment
title_full_unstemmed Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment
title_short Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment
title_sort hepatitis b-associated symptomatic iron overload, with complete resolution after nucleoside analogue treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723841/
https://www.ncbi.nlm.nih.gov/pubmed/34987872
http://dx.doi.org/10.1155/2021/8407257
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