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SIRT1 Attenuates Apoptosis of Nucleus Pulposus Cells by Targeting Interactions between LC3B and Fas under High-Magnitude Compression

Mechanical overloading-induced nucleus pulposus cell (NPC) apoptosis plays a core role in the pathogenesis of intervertebral disc degeneration. In this study, we investigated the involvement of mammalian silent information regulator 2 homolog (SIRT1) in NPC apoptosis under high-magnitude compression...

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Detalles Bibliográficos
Autores principales:	Zhuo, Yunyun, Wang, Haoming, Zou, Luetao, Wang, Yiyang, Hu, Yanzhu, Li, Pei, Zhou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723870/ https://www.ncbi.nlm.nih.gov/pubmed/34987698 http://dx.doi.org/10.1155/2021/2420969

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