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Complete loss of miR-200 family induces EMT associated cellular senescence in gastric cancer

The EMT (epithelial-to-mesenchymal-transition) subtype of gastric cancer (GC) is associated with poor treatment responses and unfavorable clinical outcomes. Despite the broad physiological roles of the micro-RNA (miR)-200 family, they largely serve to maintain the overall epithelial phenotype. Howev...

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Detalles Bibliográficos
Autores principales: Yu, Liang, Cao, Can, Li, Xu, Zhang, Mili, Gu, Qisheng, Gao, Hugh, Balic, Jesse J., Xu, Duogang, Zhang, Lei, Ying, Le, Xu, Dakang, Yang, Yuqin, Wu, Di, He, Baokun, Jenkins, Brendan J., Liu, Youdong, Li, Jikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724006/
https://www.ncbi.nlm.nih.gov/pubmed/34667277
http://dx.doi.org/10.1038/s41388-021-02067-y